Nothing major as far as I can tell. Here’s an overview via SuperUser. KeePassXC might be a better option for some use cases if you’re mostly not on Windows as it does not require .NET. Note that “KeePassXC does not support plugins at the moment and probably never will”, but it does have built-in support for some things you might want a plugin for in KeePass2.
This is why I pay for YT Premium. No way in hell am I watching ads, but I do want to be able to use the platform, and the money has to come from somewhere. So far it’s been pretty good value, although SponsorBlock is of course still required.